Description

4-(2-tert-Butoxycarbonylethyl)-Benzoic Acid is a specialized benzoic acid derivative featuring a tert-butyl ester-protected carboxylic acid side chain, making it a valuable protected intermediate in organic synthesis. This compound is crucial for researchers and manufacturers requiring precise molecular architecture, as the tert-butoxycarbonyl (Boc) group offers orthogonal protection that is stable under a wide range of reaction conditions yet can be cleanly removed. It is primarily sought after by the pharmaceutical, agrochemical, and advanced materials sectors for the development of active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex drug candidates, particularly those requiring a protected carboxylic acid functionality during multi-step sequences.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators where the benzoic acid core is a common pharmacophore.
• Liquid Crystal & Polymer Chemistry: Acts as a monomer or precursor for creating advanced organic materials with specific optical or electronic properties.
• Peptide Mimetics & Bioconjugation: The protected side chain is useful in constructing non-natural amino acids or linkers for bioconjugation strategies in drug delivery systems.
• Organic Synthesis Research: A versatile reagent for academic and industrial R&D laboratories exploring new carbon-carbon bond formation methodologies or cascade reactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules on various scales.

Basic Information

Product Name	4-(2-tert-Butoxycarbonylethyl)-Benzoic Acid
CAS No.	953435-23-9
Molecular Formula	C14H18O4
Molecular Weight	250.29 g/mol
Synonyms	4-[2-[(1,1-Dimethylethoxy)carbonyl]ethyl]benzoic acid; 4-(2-tert-Butoxycarbonylethyl)benzoic Acid; Benzoic acid, 4-[2-[(1,1-dimethylethoxy)carbonyl]ethyl]-; 4-(2-(tert-Butoxycarbonyl)ethyl)benzoic Acid; 4-(2-Boc-ethyl)benzoic Acid; 2-(4-Carboxyphenyl)ethyl tert-butyl carbonate; tert-Butyl 2-(4-carboxyphenyl)ethyl carbonate
EINECS	Contact for details

Quality Control

Our production of 4-(2-tert-Butoxycarbonylethyl)-Benzoic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization, including HPLC for purity assay and identity confirmation via spectroscopic methods (NMR, IR, MS). We provide Certificates of Analysis (COA) with detailed specifications for every shipment, supporting your quality assurance and regulatory documentation needs. For custom grades or specific impurity profiles, our technical team is available for consultation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.