Description

1-Phenyl-2-[3-(Trifluoromethyl)Anilino]-1-Ethanone is a specialized trifluoromethylated anilino ketone derivative, serving as a high-value building block in advanced organic synthesis. Its molecular structure, featuring both a phenyl ketone and a trifluoromethyl-substituted aniline moiety, makes it a critical intermediate for developing compounds with enhanced biological activity and physicochemical properties. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and development of new active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in developing advanced pesticides and herbicides, where the trifluoromethyl group can improve metabolic stability and lipophilicity.
• Material Science: Serves as a building block for creating specialty polymers and liquid crystals with unique optical or electronic properties.
• Chemical Synthesis: Employed in academic and industrial R&D for constructing complex heterocyclic compounds and fluorinated molecular architectures.
• Bioconjugation & Probe Development: Useful in the design of chemical probes and bioconjugation reagents for biochemical and diagnostic applications.

Basic Information

Product Name	1-Phenyl-2-[3-(Trifluoromethyl)Anilino]-1-Ethanone
CAS No.	952182-66-0
Molecular Formula	C15H12F3NO
Molecular Weight	279.26 g/mol
Synonyms	1-Phenyl-2-((3-(trifluoromethyl)phenyl)amino)ethan-1-one; 2-Amino-1-phenyl-1-ethanone, N-[3-(trifluoromethyl)phenyl]-; N-[3-(Trifluoromethyl)phenyl]-2-aminoacetophenone; α-[(3-Trifluoromethyl)anilino]acetophenone; 952182-66-0; Ethanone, 1-phenyl-2-[[3-(trifluoromethyl)phenyl]amino]-; 2-((3-(Trifluoromethyl)phenyl)amino)-1-phenylethanone
EINECS	Contact for details

Quality Control

Our production of 1-Phenyl-2-[3-(Trifluoromethyl)Anilino]-1-Ethanone adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure consistency and meet the exacting standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.