Description

3-(4-Bromo-3-Fluorophenyl)-2-Methylprop-1-Ene is a high-purity, halogenated aromatic building block of significant interest in advanced organic synthesis. This compound matters as a versatile intermediate, offering a reactive alkene moiety and strategically placed bromine and fluorine substituents for selective functionalization. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures. Our supply ensures consistent quality and reliable availability for critical R&D and scale-up projects.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring halogenated aromatic cores for bioactivity or metabolic stability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the bromo-fluoro-phenyl group can enhance binding affinity and environmental persistence.
• Material Science Research: Acts as a monomer or functionalization agent in the creation of specialty polymers and advanced organic electronic materials.
• Ligand and Catalyst Development: Employed to synthesize novel phosphine or N-heterocyclic carbene (NHC) ligands for transition metal catalysis.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to form biaryl systems.
• Fluorine Chemistry Studies: A valuable compound for investigating the electronic and steric effects of fluorine atoms in aromatic systems.

Basic Information

Product Name	3-(4-Bromo-3-Fluorophenyl)-2-Methylprop-1-Ene
CAS No.	951888-47-4
Molecular Formula	C10H10BrF
Molecular Weight	229.09 g/mol
Synonyms	1-(4-Bromo-3-fluorophenyl)-2-methylpropene; 2-Methyl-3-(4-bromo-3-fluorophenyl)prop-1-ene; 4-Bromo-3-fluoro-α-methylstyrene; (4-Bromo-3-fluorophenyl)-2-methylpropene; 3-(4-Bromo-3-fluorophenyl)-2-methyl-1-propene
EINECS	Contact for details

Quality Control

Our 3-(4-Bromo-3-Fluorophenyl)-2-Methylprop-1-Ene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider storing under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.