Description

1H-Imidazole-2-Methanesulfinic Acid, α-Hydroxy is a specialized, high-purity sulfinic acid derivative of the imidazole heterocycle, serving as a critical building block in advanced organic synthesis. Its unique bifunctional structure, featuring both a reactive sulfinic acid group and a hydroxylated α-carbon, makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients, chiral ligands, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting enzyme inhibition or requiring specific chiral centers.
• Agrochemical Synthesis: Building block for developing new generation herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Ligand and Catalyst Development: Used to create sophisticated chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Intermediate in the manufacture of specialty chemicals, dyes, and advanced polymer modifiers.
• Bioconjugation Chemistry: Potential use in developing linkers for antibody-drug conjugates (ADCs) or protein modification due to its reactive handles.
• Academic and R&D: Serves as a valuable reagent in organic chemistry research for methodology development and exploring new reaction pathways.

Basic Information

Product Name	1H-Imidazole-2-Methanesulfinic Acid, α-Hydroxy
CAS No.	950820-61-8
Molecular Formula	C4H6N2O3S
Molecular Weight	162.17 g/mol
Synonyms	α-Hydroxy-1H-imidazole-2-methanesulfinic Acid; 2-(Hydroxy(methylsulfinyl)methyl)-1H-imidazole; (α-Hydroxy-1H-imidazol-2-yl)methanesulfinic Acid; 1H-Imidazole-2-methanesulfinic acid, α-hydroxy-; Hydroxy(1H-imidazol-2-yl)acetic acid sulfinic acid derivative
EINECS	Contact for details

Quality Control

Every batch of 1H-Imidazole-2-Methanesulfinic Acid, α-Hydroxy is produced and tested under a strict quality management system to ensure consistency and reliability for your critical applications. We employ advanced analytical techniques, including HPLC, NMR, and mass spectrometry, to verify identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment, ensuring full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.