Description

Aurintricarboxylic Acid Trisodium Salt is a water-soluble, synthetic organic dye and a well-characterized biochemical inhibitor. This compound is valued for its specific inhibitory action against nucleases and other enzymes, making it a critical research tool in molecular biology. It is primarily utilized by research institutions, diagnostic kit manufacturers, and pharmaceutical development laboratories for applications requiring the protection of nucleic acids.

Application

• Nuclease Inhibition in Molecular Biology: Used as a potent inhibitor of ribonucleases (RNases) and deoxyribonucleases (DNases) to protect RNA and DNA during extraction, purification, and storage procedures.
• Biochemical Research Reagent: Employed in enzymatic studies to investigate the mechanisms of nucleases, topoisomerases, and integrases.
• Diagnostic Assay Component: Incorporated into diagnostic kits and buffers to prevent nucleic acid degradation, ensuring assay accuracy and stability.
• Virus Research: Studied for its inhibitory effects on the integrase enzyme of certain viruses, supporting antiviral research initiatives.
• Apoptosis Studies: Utilized in cell biology research to study apoptotic pathways due to its interaction with specific cellular enzymes.
• Histological Staining: Acts as a biological stain in certain microscopic applications for tissue and cell analysis.

Basic Information

Product Name	Aurintricarboxylic Acid Trisodium Salt
CAS No.	13186-45-3
Molecular Formula	C22H14Na3O9
Molecular Weight	514.31 g/mol
Synonyms	Aluminon Trisodium Salt; ATA; Ammonium Aurintricarboxylate; Aurintricarboxylic Acid Ammonium Salt; 5-[(3-Carboxy-4-oxidophenyl)(3-carboxy-4-oxocyclohexa-2,5-dien-1-ylidene)methyl]-2-hydroxybenzoic Acid Trisodium Salt; CI 43810; NSC 405124; 1,1'-[(3-Carboxy-4-oxophenyl)methylene]bis[2-hydroxy-5-benzoic acid] Trisodium Salt
EINECS	236-149-5

Quality Control

Our Aurintricarboxylic Acid Trisodium Salt is manufactured under a rigorous quality management system. Each batch is tested to ensure high purity and consistent performance as a biochemical reagent. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided to guarantee it meets the stringent requirements of research and diagnostic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	Dark red to brownish-red powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Loss on Drying	≤ 5.0%
Water Solubility	Freely soluble
pH (1% Solution)	7.0 - 9.0
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.