Description

2,2'-Dithiobis(5-Nitrobenzoic Acid) is a specialized aromatic disulfide derivative with a nitro-substituted benzoic acid structure. This compound is valued for its role as a key intermediate and reagent in advanced organic synthesis and biochemical research. It is primarily sought by professionals in the pharmaceutical, agrochemical, and fine chemical industries for developing novel compounds and analytical applications.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring disulfide or nitro-aromatic motifs.
• Biochemical Research Reagent: Serves as a precursor or derivatization agent in proteomics and enzyme activity studies, often related to thiol/disulfide exchange reactions.
• Agrochemical Synthesis: An important building block for creating novel herbicides, fungicides, and plant growth regulators.
• Polymer Chemistry: Acts as a cross-linking agent or chain transfer agent in the production of specialty polymers and resins.
• Analytical Chemistry: Employed as a standard or reagent in chromatographic methods and spectrophotometric assays for thiol quantification (e.g., Ellman's reagent analog).
• Material Science: Investigated for use in creating self-assembled monolayers (SAMs) and functionalized surfaces on metals.

Basic Information

Product Name	2,2'-Dithiobis(5-Nitrobenzoic Acid)
CAS No.	1170-38-3
Molecular Formula	C14H8N2O8S2
Molecular Weight	404.35 g/mol
Synonyms	5,5'-Dithiobis(2-nitrobenzoic acid); DTNB; Ellman's Reagent (related compound); Bis(5-carboxy-2-nitrophenyl) disulfide; 2-Nitro-5-mercaptobenzoic acid disulfide; Aldrithiol-4; 4,4'-Dithiodinitrobenzoic acid; DNBS disulfide
EINECS	214-571-1

Quality Control

Our 2,2'-Dithiobis(5-Nitrobenzoic Acid) is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production standards. Custom purity grades, including analytical and pharmaceutical reference standards, are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is light-sensitive (store away from light). Keep away from heat, sparks, and open flame. For long-term storage, consider inert gas purging to minimize potential oxidative degradation.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	240 - 245 °C (dec.)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.