Description

4-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]-2,3-Dihydro-1H-Naphtho[1,8-De][1,3,2]Diazaborinine is a sophisticated, high-purity organoboron compound that serves as a critical building block in advanced organic synthesis. Its unique fused-ring diazaborinine structure, coupled with a pinacol boronate ester functional group, makes it a versatile and valuable intermediate for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require precise, high-quality boron-containing precursors for cross-coupling reactions and the development of novel functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly in oncology and CNS research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require complex boron-heterocycle motifs for enhanced activity.
• Organic Light-Emitting Diodes (OLEDs): Serves as a building block for electron-transport materials and host molecules in OLED displays and lighting due to its rigid, conjugated structure.
• Polymer & Materials Science: Incorporated into specialty polymers, liquid crystals, and organic semiconductors to modify electronic properties and thermal stability.
• Chemical Biology Probes: Utilized in the synthesis of bioconjugates and probes for studying biological processes and enzyme activity.
• Catalyst & Ligand Development: Acts as a precursor for novel N,B-chelating ligands used in transition metal catalysis.

Basic Information

Product Name	4-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]-2,3-Dihydro-1H-Naphtho[1,8-De][1,3,2]Diazaborinine
CAS No.	950511-16-7
Molecular Formula	C24H28B2N2O2
Molecular Weight	398.12 g/mol
Synonyms	2-(4-(2,3-Dihydro-1H-naphtho[1,8-de][1,3,2]diazaborinin-4-yl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-2,3-dihydro-1H-naphtho[1,8-de][1,3,2]diazaborinine; Naphtho[1,8-de][1,3,2]diazaborinine Boronic Acid Pinacol Ester Derivative; Borylated Naphthodiazaborinine; BN-Naphthodiazaborinine Pinacol Ester
EINECS	Contact for details

Quality Control

Our production of 4-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]-2,3-Dihydro-1H-Naphtho[1,8-De][1,3,2]Diazaborinine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR (1H, 13C, 11B), and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We support cGMP-compliant manufacturing for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent moisture absorption and decomposition. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.