Description

Phosphinic Acid, p-(Hydroxy-1H-Imidazol-5-Ylmethyl)- (CAS 949115-53-1) is a specialized organophosphorus compound featuring a unique imidazole-phosphinic acid hybrid structure. This molecular architecture makes it a valuable intermediate for synthesizing novel chelating agents, pharmaceutical candidates, and functional materials. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating compounds with targeted biological or catalytic activity.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting enzymes or receptors where the imidazole and phosphinic acid moieties can act as pharmacophores or metal-binding groups.
• Agrochemical Research: Used in developing new herbicides, fungicides, or plant growth regulators that leverage its unique chemical reactivity and potential for systemic activity.
• Ligand & Chelator Synthesis: Serves as a precursor for creating sophisticated multidentate ligands used in catalysis, metal extraction, or as contrast agents in medical imaging.
• Material Science: Potential monomer or additive for creating polymers with specific flame-retardant, adhesive, or metal-adhesion properties due to the phosphorus content.
• Biochemical Tool Compound: Used in academic and industrial research to study enzyme inhibition, particularly for metalloenzymes, due to the phosphinic acid group's ability to mimic transition states.

Basic Information

Product Name	Phosphinic Acid, p-(Hydroxy-1H-Imidazol-5-Ylmethyl)-
CAS No.	949115-53-1
Molecular Formula	C4H7N2O3P
Molecular Weight	162.08 g/mol
Synonyms	4-(Hydroxy-1H-imidazol-5-ylmethyl)phosphinic acid; 5-(Hydroxymethyl)-1H-imidazole-4-phosphinic acid; p-(Hydroxy-1H-imidazol-5-ylmethyl)phosphinic acid; 1H-Imidazole-4-methanol, 5-phosphino-; Phosphinic acid, P-[4-(hydroxymethyl)-1H-imidazol-5-yl]-
EINECS	Contact for details

Quality Control

Every batch of Phosphinic Acid, p-(Hydroxy-1H-Imidazol-5-Ylmethyl)- is produced and analyzed under strict quality management protocols. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical R&D and scale-up processes. Certificates of Analysis (COA) detailing purity (typically by HPLC or titration), identity confirmation (by IR, NMR), and impurity profiles are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.