Description

Tri-tert-Butylphosphine is a highly reactive tertiary phosphine ligand prized for its exceptional electron-donating properties and steric bulk. This compound is a critical catalyst component in cross-coupling reactions, enabling efficient carbon-carbon and carbon-heteroatom bond formation. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-performance catalytic systems for complex organic synthesis.

Application

• Catalyst Ligand in Cross-Coupling Reactions: A key component in Buchwald-Hartwig amination, Suzuki-Miyaura, and Negishi couplings for pharmaceutical intermediate synthesis.
• Polymerization Catalyst: Used as a ligand in late-transition metal catalysts for olefin polymerization and copolymerization.
• Hydrosilylation Reactions: Employed in catalysts for the addition of silicon-hydrogen bonds to unsaturated organic compounds.
• Hydrogenation Catalysis: Acts as a ligand for precious metal catalysts in selective hydrogenation processes.
• Organic Light-Emitting Diode (OLED) Material Synthesis: Facilitates the production of complex organic molecules used in electronic materials.
• Agrochemical Active Ingredient Synthesis: Enables the construction of complex molecular architectures in crop protection agents.
• Academic and Industrial R&D: A valuable reagent for methodological development in organometallic chemistry and catalysis.

Basic Information

Product Name	Tri-tert-Butylphosphine
CAS No.	13716-12-6
Molecular Formula	C12H27P
Molecular Weight	202.32 g/mol
Synonyms	Tris(tert-butyl)phosphine; Tri-tert-butylphosphane; P(t-Bu)3; TTBP; Phosphorous tri-tert-butyl; Tris(1,1-dimethylethyl)phosphine; (tert-Bu)3P; 2-Methyl-2-propanephosphine, 1,1',1''-phosphinylidynetris-
EINECS	237-283-2

Quality Control

Our Tri-tert-Butylphosphine is manufactured under stringent quality management systems. Each batch undergoes rigorous analytical testing, including NMR, GC, and titration, to ensure high purity and consistency. Certificates of Analysis (COA) detailing specific batch results are provided and available upon request. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store under an inert atmosphere (argon or nitrogen) at a controlled room temperature (15-25°C). Due to its air-sensitive and easily oxidized nature, containers must be kept sealed and handled in a glove box or under a continuous inert gas purge when accessed.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 97.0%
Assay (Titration)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.