Description

Di-o-Tolylchlorophosphine is a specialized organophosphorus compound featuring two ortho-tolyl groups and a reactive phosphorus-chlorine bond. This structure makes it a valuable key intermediate in the synthesis of complex ligands and catalysts, particularly in asymmetric synthesis and transition metal chemistry. It is essential for R&D and production in the pharmaceutical, agrochemical, and advanced materials sectors, where precise molecular architecture is critical.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing novel active pharmaceutical ingredients (APIs), especially those requiring chiral phosphine ligands.
• Catalyst & Ligand Synthesis: Serves as a precursor for manufacturing sophisticated phosphine ligands used in cross-coupling reactions (e.g., Suzuki, Heck) and homogeneous catalysis.
• Agrochemical Production: Used in the development of advanced herbicides, insecticides, and fungicides that incorporate organophosphorus moieties for enhanced efficacy.
• Material Science Research: Employed in the creation of novel polymers, flame retardants, and electronic materials where phosphorus-based modifiers are needed.
• Organic Synthesis Reagent: Acts as a phosphorylating or chlorinating agent in the preparation of various phosphorus-containing organic compounds.

Basic Information

Product Name	Di-o-Tolylchlorophosphine
CAS No.	36042-94-1
Molecular Formula	C14H14ClP
Molecular Weight	248.68 g/mol
Synonyms	Chlorodi-o-tolylphosphine; Di(2-methylphenyl)chlorophosphine; Di(2-tolyl)chlorophosphine; o-Tolylphosphonous Dichloride (related); Phosphinous chloride, P,P-di-2-tolyl-; 2-Methylphenylphosphonous dichloride (precursor); Dichloro(o-tolyl)phosphine (related compound); DTCP
EINECS	Contact for details

Quality Control

Our Di-o-Tolylchlorophosphine is produced under stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including NMR, HPLC, and GC analysis, to ensure high purity and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with specified standards. Our commitment to traceability and reliability supports critical applications in pharmaceutical and fine chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. This material is moisture-sensitive and highly volatile; keep away from heat, sparks, and open flames. Isolate from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Chloride Content	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.