Description

Methyl 3-Chloro-2,4-Difluorobenzoate is a high-purity fluorinated aromatic ester serving as a critical building block in advanced organic synthesis. This compound matters for its role in constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific halogenated motifs into their target structures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially those containing difluorobenzene and chlorobenzene pharmacophores.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the halogenated benzoate structure imparts specific biological activity.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for display technologies.
• Polymer Chemistry: Employed as a monomer or modifying agent to introduce fluorine and chlorine functionalities into specialty polymers, enhancing their chemical resistance and stability.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic substitution reactions to create complex, multi-substituted aromatic systems.
• Material Science Research: Acts as a starting material for developing novel organic electronic materials and coatings.

Basic Information

Product Name	Methyl 3-Chloro-2,4-Difluorobenzoate
CAS No.	948833-74-7
Molecular Formula	C8H5ClF2O2
Molecular Weight	206.57 g/mol
Synonyms	3-Chloro-2,4-difluorobenzoic acid methyl ester; Methyl 3-chloro-2,4-difluorobenzoate; Benzoic acid, 3-chloro-2,4-difluoro-, methyl ester; 2,4-Difluoro-3-chlorobenzoic acid methyl ester; Methyl 3-chloro-2,4-difluorobenzenecarboxylate; 948833-74-7; Methyl 3-chloro-2,4-difluorobenzoate (CAS 948833-74-7)
EINECS	Contact for details

Quality Control

Our Methyl 3-Chloro-2,4-Difluorobenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurity profiles, and physical characteristics are provided with every shipment to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.