Description

(S)-4-Chloro-1,2-Epoxybutane is a high-value chiral epoxide building block of significant importance in asymmetric synthesis. This optically active intermediate is critical for the production of advanced pharmaceutical compounds and fine chemicals, enabling the construction of complex molecular architectures with high stereochemical fidelity. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active pharmaceutical ingredients (APIs) and other high-performance materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of β-blockers, antiviral agents, and other bioactive molecules requiring specific stereochemistry.
• Agrochemical Synthesis: Used in the production of chiral herbicides, fungicides, and plant growth regulators.
• Liquid Crystal & Polymer Chemistry: Serves as a monomer or precursor for creating optically active polymers and advanced materials with specific chiral properties.
• Asymmetric Catalysis Research: Employed as a standard substrate in the development and testing of new chiral catalysts and synthetic methodologies.
• Fine Chemical Production: Integral for manufacturing specialty chemicals, flavors, and fragrances where enantiomeric purity is essential.

Basic Information

Product Name	(S)-4-Chloro-1,2-Epoxybutane
CAS No.	948594-94-3
Molecular Formula	C4H7ClO
Molecular Weight	106.55 g/mol
Synonyms	(S)-(-)-4-Chloro-1,2-epoxybutane; (S)-1-Chloro-3,4-epoxybutane; (S)-4-Chloro-1,2-butylene oxide; (S)-Epichlorohydrin homologue; (2S)-2-[(Chloromethyl)oxirane]; (S)-Glycidyl chloride homologue; (S)-1,2-Epoxy-4-chlorobutane; (S)-4-Chlorooxirane-2-ylmethane
EINECS	Contact for details

Quality Control

Our (S)-4-Chloro-1,2-Epoxybutane is manufactured under strict quality management systems. Each batch is characterized and tested to ensure high chemical and enantiomeric purity, meeting the stringent requirements for advanced synthetic applications. Comprehensive analytical methods including HPLC, GC, and chiral analysis are employed. A Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.