Description

(2S 3S)-(-)-3-(4-Nitrophenyl)Glycidol CAS NO 1885-07-0 is a high-purity chiral epoxide building block of significant synthetic utility. This compound is valued for its role as a key intermediate in the enantioselective synthesis of complex pharmaceutical molecules and fine chemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material industries for constructing molecules with defined stereochemistry.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring specific (2S,3S) stereochemistry.
• Asymmetric Synthesis: Used in the preparation of chiral ligands, catalysts, and auxiliaries for stereoselective transformations.
• Agrochemical Research: Serves as a building block for developing novel, enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances where optical purity is essential.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry programs.
• Material Science Precursor: Potential use in synthesizing chiral monomers for advanced polymeric materials.

Basic Information

Product Name	(2S 3S)-(-)-3-(4-Nitrophenyl)Glycidol
CAS No.	1885-07-0
Molecular Formula	C9H9NO4
Molecular Weight	195.17 g/mol
Synonyms	(-)-(2S,3S)-3-(4-Nitrophenyl)glycidol; (2S,3S)-3-(4-Nitrophenyl)oxiranemethanol; (2S,3S)-(-)-3-(p-Nitrophenyl)glycidol; (2S,3S)-3-(4-Nitrophenyl)-2-oxiranemethanol; 4-Nitro-α-[(2S,3S)-oxiranyl]benzenemethanol; (2S,3S)-3-(4-Nitrophenyl)glycidyl alcohol; Chiral 4-nitrophenyl glycidol
EINECS	Contact for details

Quality Control

Our (2S 3S)-(-)-3-(4-Nitrophenyl)Glycidol is produced under strict quality management protocols to ensure batch-to-batch consistency and high enantiomeric purity. We provide comprehensive analytical data, including chiral HPLC or GC analysis to confirm stereochemical integrity. Certificates of Analysis (COA) detailing purity, assay, and specific rotation are available for every batch upon request, supporting your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Specific Rotation	Contact for details
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.