Description

(R)-(+)-Propylene Oxide is the enantiomerically pure, right-handed (R) isomer of propylene oxide, a highly versatile chiral epoxide. This specific stereochemistry is critical for synthesizing optically active intermediates and final products, where the absolute configuration directly influences biological activity and material properties. It is an essential building block for advanced pharmaceutical synthesis, chiral ligand development, and the production of specialty polymers and fine chemicals requiring precise stereocontrol.

Application

• Chiral Pharmaceutical Intermediates: Key starting material for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), including β-blockers, antifungals, and antiviral agents.
• Asymmetric Synthesis & Catalysis: Used in the preparation of chiral catalysts, ligands (e.g., for asymmetric epoxidation), and auxiliaries crucial for stereoselective chemical transformations.
• Specialty Polymerization: Monomer for producing chiral polyethers and polyols with tailored physical properties for advanced material science applications.
• Fine Chemical Synthesis: Intermediate in the manufacture of chiral agrochemicals, flavors, fragrances, and liquid crystals.
• Derivatization Agent: Employed in analytical chemistry for chiral derivatization to separate and analyze enantiomers via chromatography.
• Cross-linking and Functionalization: Used to introduce reactive epoxide groups onto polymers, surfaces, or biomolecules for further modification.

Basic Information

Product Name	(R)-(+)-Propylene Oxide
CAS No.	15448-47-2
Molecular Formula	C3H6O
Molecular Weight	58.08 g/mol
Synonyms	(R)-Propylene Oxide; (R)-(+)-Methyloxirane; (R)-1,2-Epoxypropane; (R)-Methyl Ethylene Oxide; (R)-Propene Oxide; (R)-PO; (+)-(R)-Propylene Oxide; (2R)-2-Methyloxirane
EINECS	Contact for details

Quality Control

Our (R)-(+)-Propylene Oxide is produced under stringent conditions to ensure high enantiomeric purity and chemical integrity. Each batch is subjected to comprehensive analytical testing, including chiral GC or HPLC to confirm enantiomeric excess (ee), identity verification, and impurity profiling. A Certificate of Analysis (COA) detailing purity, specific rotation, and key specifications is provided with every shipment, ensuring compliance with rigorous internal standards suitable for research and industrial synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat, sparks, and open flames. Due to its highly volatile and flammable nature, keep container tightly sealed when not in use. Recommended storage temperature is 2-8°C to maximize stability. Keep away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless liquid
Identification (IR)	Conforms
Purity (GC)	≥ 98.0%
Enantiomeric Excess (ee)	≥ 99.0%
Specific Rotation [α]D20	+14.0° to +16.0° (neat)
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.