Description

n-Methyl-3,5-Bis-Trifluoromethyl-Benzamide is a high-value fluorinated aromatic building block characterized by its trifluoromethyl groups and amide functionality. This compound is critical for introducing lipophilicity and metabolic stability into target molecules, making it a sought-after intermediate in advanced chemical synthesis. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides and pesticides, where the trifluoromethyl groups enhance biological activity and environmental persistence.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals, contributing unique electronic and surface properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions and as a scaffold for constructing complex, fluorinated heterocycles in medicinal chemistry.
• Chemical Biology Probes: Utilized in the design of molecular probes and inhibitors for studying enzyme function and protein-ligand interactions.

Basic Information

Product Name	n-Methyl-3,5-Bis-Trifluoromethyl-Benzamide
CAS No.	948294-23-3
Molecular Formula	C11H7F6NO
Molecular Weight	283.17 g/mol
Synonyms	N-Methyl-3,5-bis(trifluoromethyl)benzamide; 3,5-Bis(trifluoromethyl)-N-methylbenzamide; Benzamide, N-methyl-3,5-bis(trifluoromethyl)-; 948294-23-3; N-Methyl-3,5-di(trifluoromethyl)benzamide; N-Methyl-α,α,α,α',α',α'-hexafluoro-3,5-xylene-α-carboxamide
EINECS	Contact for details

Quality Control

Our n-Methyl-3,5-Bis-Trifluoromethyl-Benzamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and fluorides. The container must be kept tightly closed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.