Description

(3-Bromobenzyl)-Cyanoacetic Acid is a versatile bifunctional organic building block that combines a reactive cyanoacetate moiety with a brominated benzyl group. This molecular architecture makes it a critical intermediate for the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists for constructing novel compounds via nucleophilic substitution and Knoevenagel condensation reactions. Its reliable quality and consistent supply are essential for accelerating drug discovery pipelines and material science projects.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a precursor for functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology: Employed in the design and synthesis of molecular probes and enzyme inhibitors for biochemical research.
• Fine Chemical Production: Intermediate for manufacturing dyes, pigments, and other specialty chemicals requiring a bromoaryl motif.
• Cross-Coupling Reactions: The bromine atom makes it a suitable substrate for palladium-catalyzed reactions like Suzuki-Miyaura and Buchwald-Hartwig amination.

Basic Information

Product Name	(3-Bromobenzyl)-Cyanoacetic Acid
CAS No.	948015-61-0
Molecular Formula	C10H8BrNO2
Molecular Weight	254.08 g/mol
Synonyms	2-Cyano-2-(3-bromobenzyl)acetic Acid; (3-Bromobenzyl)cyanoacetic Acid; 2-(3-Bromobenzyl)-2-cyanoacetic Acid; α-Cyano-3-bromobenzylacetic Acid; 3-Bromobenzylmalononitrile Acid; NSC 781106; (3-Bromophenylmethyl)cyanoacetic Acid
EINECS	Contact for details

Quality Control

Every batch of (3-Bromobenzyl)-Cyanoacetic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.