Description

4-Hydroxyphenylacetic Acid is a versatile phenolic acid derivative that serves as a critical building block in organic synthesis and pharmaceutical manufacturing. Its bifunctional structure, featuring both a phenolic hydroxyl and a carboxylic acid group, makes it a valuable intermediate for creating more complex molecules. This compound is essential for industries focused on developing active pharmaceutical ingredients (APIs), fine chemicals, and advanced research materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various drugs, including β-blockers (e.g., atenolol), bronchodilators, and other cardiovascular agents.
• Fine Chemical Synthesis: Used as a starting material or intermediate for producing specialty chemicals, agrochemicals, and dyes.
• Biochemical Research: Employed in enzymatic studies and as a standard or reagent in analytical laboratories for method development.
• Flavor and Fragrance Industry: Serves as a building block for certain aroma compounds and synthetic flavors.
• Polymer Chemistry: Can be incorporated into polymer chains to introduce phenolic functionality, modifying material properties.
• Cosmetic Ingredients: Potential intermediate in the synthesis of UV absorbers or antioxidant agents for personal care formulations.

Basic Information

Product Name	4-Hydroxyphenylacetic Acid
CAS No.	156-38-7
Molecular Formula	C8H8O3
Molecular Weight	152.15 g/mol
Synonyms	(4-Hydroxyphenyl)acetic Acid; p-Hydroxyphenylacetic Acid; 2-(4-Hydroxyphenyl)acetic Acid; 4-Hydroxybenzeneacetic Acid; PHPA; HPA; Para-Hydroxyphenylacetic Acid; 4-Hydroxybenzylcarboxylic Acid
EINECS	205-851-5

Quality Control

Our 4-Hydroxyphenylacetic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting specifications for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) are provided with every shipment, detailing all relevant parameters to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	148°C - 152°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.