Description

(4-Bromo-Benzyl)-Cyano-Acetic Acid is a versatile brominated aromatic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a reactive cyanoacetic acid moiety and a bromobenzyl group, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides and pesticides, where the bromine atom allows for further functionalization.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for metal-catalyzed cross-coupling reactions, such as Suzuki or Heck reactions.
• Material Science Research: Acts as a monomer or functionalizing agent in the synthesis of advanced polymers and organic electronic materials.
• Chemical Biology Probes: Utilized to develop molecular probes and tags for studying biological processes and protein interactions.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis houses producing high-value, low-volume specialty chemicals for diverse clients.

Basic Information

Product Name	(4-Bromo-Benzyl)-Cyano-Acetic Acid
CAS No.	948015-59-6
Molecular Formula	C10H8BrNO2
Molecular Weight	254.08 g/mol
Synonyms	2-Cyano-2-(4-bromophenyl)acetic acid; (4-Bromobenzyl)cyanoacetic acid; 2-(4-Bromobenzyl)-2-cyanoacetic acid; 4-Bromobenzylcyanoacetic acid; α-Cyano-4-bromobenzylacetic acid; NSC 405124; p-Bromobenzylcyanoacetic acid; (p-Bromobenzyl)cyanoacetic acid
EINECS	Contact for details

Quality Control

Our (4-Bromo-Benzyl)-Cyano-Acetic Acid is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.