Description

3-(4-Chloro-2-Fluorophenoxy)Piperidine is a high-value, fluorinated piperidine derivative used as a key synthetic intermediate in advanced organic chemistry. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific phenoxy-piperidine motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of potential drug candidates, especially in central nervous system (CNS) and metabolic disorder research.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and fungicides that require fluorinated phenoxy compounds.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the design of molecular probes for studying enzyme inhibition and receptor binding.
• Material Science Research: Acts as a monomer or functionalizing agent in the development of advanced polymers with specific electronic or surface properties.

Basic Information

Product Name	3-(4-Chloro-2-Fluorophenoxy)Piperidine
CAS No.	946726-21-2
Molecular Formula	C11H13ClFNO
Molecular Weight	229.68 g/mol
Synonyms	3-[(4-Chloro-2-fluorophenyl)oxy]piperidine; Piperidine, 3-[(4-chloro-2-fluorophenoxy)]-; 4-Chloro-2-fluoro-3-piperidinyloxybenzene; 3-(4-Chloro-2-fluorophenoxy)piperidine; 946726-21-2; 3-(4-Chloro-2-fluoro-phenoxy)-piperidine
EINECS	Contact for details

Quality Control

Every batch of 3-(4-Chloro-2-Fluorophenoxy)Piperidine is produced under strict quality management systems. We employ advanced analytical techniques, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to minimize exposure to moisture and atmospheric oxygen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.