Description

5-Chloro-2-(3,4-Difluorophenoxy)Aniline is a high-value, multi-functional aromatic amine intermediate of significant importance in advanced organic synthesis. Its core value lies in its unique molecular scaffold, which incorporates halogen and ether functionalities, making it a versatile building block for creating complex molecules. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing antimicrobial properties.
• Agrochemical Synthesis: Serves as a critical building block for developing new-generation herbicides, fungicides, and insecticides, leveraging its halogenated phenoxy aniline structure.
• Material Science Research: Used in the development of specialty polymers, liquid crystals, and advanced organic electronic materials due to its rigid, substituted aromatic core.
• Dye and Pigment Intermediate: Functions as a starting material for synthesizing complex azo dyes and high-performance pigments.
• Cross-Coupling Reactions: An essential substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) for creating complex biaryl amines.

Basic Information

Product Name	5-Chloro-2-(3,4-Difluorophenoxy)Aniline
CAS No.	946714-90-5
Molecular Formula	C12H8ClF2NO
Molecular Weight	255.65 g/mol
Synonyms	5-Chloro-2-(3,4-difluorophenoxy)benzenamine; 2-Amino-4-chloro-1-(3,4-difluorophenoxy)benzene; Benzenamine, 5-chloro-2-(3,4-difluorophenoxy)-; 946714-90-5; 5-Chloro-2-(3,4-difluorophenoxy)phenylamine
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-(3,4-Difluorophenoxy)Aniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and scale-up applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled under an inert atmosphere for long-term storage to prevent potential oxidation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.