Description

4-Aminophenylacetic Acid is a key aromatic amino acid derivative that serves as a versatile building block in advanced organic synthesis. Its bifunctional structure, featuring both an aromatic amine and a carboxylic acid group, makes it a critical intermediate for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for the development of active pharmaceutical ingredients (APIs) and specialized biochemical reagents.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various drug candidates and active pharmaceutical ingredients (APIs), including potential anti-inflammatory and analgesic agents.
• Peptide Synthesis: Used as a protected or unprotected amino acid derivative for the solid-phase and solution-phase synthesis of novel peptides and peptidomimetics.
• Bioconjugation & Linker Chemistry: Employed in the creation of chemical linkers and spacers for antibody-drug conjugates (ADCs) and other bioconjugation applications.
• Agrochemical Synthesis: Serves as a building block for developing advanced herbicides, fungicides, and plant growth regulators.
• Dye & Pigment Manufacturing: Acts as an intermediate in the production of azo dyes and other specialized colorants.
• Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new chemical entities and reaction pathways.
• Material Science: Used in the synthesis of monomers for specialty polymers and advanced functional materials.

Basic Information

Product Name	4-Aminophenylacetic Acid
CAS No.	1197-55-3
Molecular Formula	C8H9NO2
Molecular Weight	151.16 g/mol
Synonyms	(4-Aminophenyl)acetic Acid; 4-Aminobenzeneacetic Acid; p-Aminophenylacetic Acid; 2-(4-Aminophenyl)acetic Acid; 4-Amino-α-toluic Acid; USAF EK-7115; NSC 403697; p-Aminohydrocinnamic Acid
EINECS	214-825-7

Quality Control

Our 4-Aminophenylacetic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure it meets the high-purity standards required for pharmaceutical and research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to ensure consistent quality and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	198°C - 202°C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.