Description

1-(Aminomethyl)-4-Chloro-2,3-Dihydroinden-1-Ol is a specialized chiral indane derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both an aminomethyl and a chloro substituent on a dihydroindenol scaffold, makes it a valuable building block for constructing complex molecules with high stereochemical fidelity. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and cardiovascular drug discovery programs.
• Agrochemical Synthesis: Used in the production of advanced crop protection chemicals, where its structural motifs can contribute to herbicidal or insecticidal activity.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or building block for specialty polymers and advanced organic materials with specific optical or electronic properties.
• Chemical Biology Probes: Employed in the synthesis of molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	1-(Aminomethyl)-4-Chloro-2,3-Dihydroinden-1-Ol
CAS No.	1082563-13-0
Molecular Formula	C10H12ClNO
Molecular Weight	197.66 g/mol
Synonyms	4-Chloro-1-(aminomethyl)-2,3-dihydro-1H-inden-1-ol; 4-Chloro-1-(aminomethyl)indan-1-ol; 1H-Inden-1-ol, 4-chloro-1-(aminomethyl)-2,3-dihydro-; (1R/S)-1-(Aminomethyl)-4-chloro-2,3-dihydro-1H-inden-1-ol (racemic mixture); 1082563-13-0; 4-Chloro-1-(aminomethyl)indan-1-ol; Amino-methyl-chloro-dihydroindenol
EINECS	Contact for details

Quality Control

Our production of 1-(Aminomethyl)-4-Chloro-2,3-Dihydroinden-1-Ol adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity (where applicable), and impurity profiles is provided with every shipment to support your critical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	Contact for details (typically supplied as racemate)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.