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4-(4-Fluorophenoxy)-3-Methylaniline CAS NO 946663-67-8


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CAS No.:946663-67-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4-(4-Fluorophenoxy)-3-Methylaniline is a high-purity aromatic amine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular structure, which combines a fluorinated phenoxy group with a methyl-substituted aniline, enabling precise chemical modifications. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
  • Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and pesticides, leveraging the fluorine moiety for enhanced bioactivity and stability.
  • Material Science Research: Acts as a monomer or functionalizing agent in the development of specialty polymers, liquid crystals, and advanced organic electronic materials.
  • Dye and Pigment Manufacturing: Serves as an intermediate for producing complex, high-performance dyes and organic pigments.
  • Cross-Coupling Reactions: An important substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) for constructing complex nitrogen-containing heterocycles.

Basic Information

Product Name 4-(4-Fluorophenoxy)-3-Methylaniline
CAS No. 946663-67-8
Molecular Formula C13H12FNO
Molecular Weight 217.24 g/mol
Synonyms 3-Methyl-4-(4-fluorophenoxy)aniline; Benzenamine, 4-(4-fluorophenoxy)-3-methyl-; 4-(4-Fluorophenoxy)-3-methylbenzenamine; 3-Methyl-4-(p-fluorophenoxy)aniline; 4-Amino-2-methylphenyl 4-fluorophenyl ether
EINECS Contact for details

Quality Control

Our 4-(4-Fluorophenoxy)-3-Methylaniline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong oxidizing agents.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Melting Point Contact for details
Loss on Drying ≤ 0.5%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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