Description

(S)-Boroleu-(-)-Pinanediol-Hydrochloride CAS NO 945606-99-5 is a high-purity, chiral organoboron reagent used as a critical intermediate in advanced synthetic chemistry. This compound is valued for its role in facilitating stereoselective transformations, particularly in the synthesis of complex pharmaceutical molecules and fine chemicals. It is essential for research and development laboratories, process chemists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to build molecular complexity with high enantiomeric fidelity.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of active pharmaceutical ingredients (APIs), especially for neurologically active compounds and enzyme inhibitors.
• Asymmetric Synthesis: Employed in Suzuki-Miyaura and other cross-coupling reactions to introduce chiral centers with high stereocontrol.
• Medicinal Chemistry Research: Used in drug discovery programs for the construction and diversification of compound libraries targeting various disease pathways.
• Agrochemical Synthesis: Serves as an intermediate in the production of chiral pesticides and herbicides with enhanced biological activity and environmental profile.
• Ligand and Catalyst Development: Utilized in the preparation of novel chiral ligands and catalysts for homogeneous catalysis.
• Process Chemistry & Scale-Up: Applied in the development and optimization of commercial-scale manufacturing routes for chiral molecules.

Basic Information

Product Name	(S)-Boroleu-(-)-Pinanediol-Hydrochloride
CAS No.	945606-99-5
Molecular Formula	C₁₆H₂₈BClO₂
Molecular Weight	298.66 g/mol
Synonyms	(S)-(-)-Pinanediol Leucineboronic Acid Hydrochloride; (S)-Leucineboronic Acid Pinanediol Ester Hydrochloride; (S)-4-Amino-2-methyl-1-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)butyl Pinanediol Boronate Hydrochloride; B-Leu(OBpin)-OH.HCl; (S)-α-Aminoboronic Acid Pinanediol Ester Hydrochloride (Leucine Derivative); L-Leucineboronic Acid Pinanediol Ester Hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-Boroleu-(-)-Pinanediol-Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC, NMR, and elemental analysis, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon or nitrogen) when possible to maintain stability and purity. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.