Description

1-(2,2,2-Trifluoroethyl)Cyclobutane-1-Carboxylic Acid is a high-value fluorinated cyclobutane derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring a cyclobutane ring and a trifluoroethyl group, makes it an essential intermediate for creating novel compounds with tailored properties. This chemical is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for introducing fluorine atoms to modulate bioavailability, metabolic stability, and binding affinity.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the fluorinated cyclobutane moiety can enhance activity and environmental profile.
• Material Science Research: Employed in the synthesis of specialty polymers, liquid crystals, or organic electronic materials that benefit from fluorinated components.
• Chemical Biology & Probe Development: Serves as a versatile scaffold for constructing molecular probes and tools used in biochemical and diagnostic research.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for fine chemical manufacturers offering bespoke synthesis services to clients in various high-tech sectors.

Basic Information

Product Name	1-(2,2,2-Trifluoroethyl)Cyclobutane-1-Carboxylic Acid
CAS No.	945495-63-6
Molecular Formula	C7H9F3O2
Molecular Weight	182.14 g/mol
Synonyms	1-(2,2,2-Trifluoroethyl)cyclobutane-1-carboxylic acid; 1-(Trifluoroethyl)cyclobutane-1-carboxylic Acid; Cyclobutane-1-carboxylic acid, 1-(2,2,2-trifluoroethyl)-; 945495-63-6; 1-(2,2,2-Trifluoroethyl)-1-cyclobutanecarboxylic acid; 1-Cyclobutanecarboxylic acid, 1-(2,2,2-trifluoroethyl)-
EINECS	Contact for details

Quality Control

Our production of 1-(2,2,2-Trifluoroethyl)Cyclobutane-1-Carboxylic Acid adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and development applications. All materials are characterized using advanced analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. For long-term storage, it is recommended to keep the material at 2-8°C under an inert atmosphere. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.