Description

1-(6-Fluorobenzo[D][1,3]Dioxol-5-Yl)Cyclopropanecarboxylic Acid is a high-purity, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique bicyclic and cyclopropane structure imparts specific biological and physicochemical properties. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to innovate new molecular entities.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and environmental stability.
• Chemical Biology Probe Synthesis: Serves as a versatile scaffold for creating molecular probes to study enzyme function and biological pathways.
• Material Science Precursor: Potential intermediate for synthesizing specialty polymers or liquid crystals with tailored electronic or optical properties.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process scale-up for client projects.
• Academic Research: Utilized in university and institutional labs for methodological studies in fluorination chemistry and cyclopropane ring transformations.

Basic Information

Product Name	1-(6-Fluorobenzo[D][1,3]Dioxol-5-Yl)Cyclopropanecarboxylic Acid
CAS No.	945244-45-1
Molecular Formula	C11H9FO4
Molecular Weight	224.19 g/mol
Synonyms	1-(6-Fluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxylic acid; 1-(6-Fluoro-1,3-benzodioxol-5-yl)cyclopropanecarboxylic acid; 5-(1-Carboxycyclopropyl)-6-fluorobenzo[d][1,3]dioxole; 6-Fluoro-5-(1-carboxycyclopropyl)-1,3-benzodioxole; Cyclopropanecarboxylic acid, 1-(6-fluoro-1,3-benzodioxol-5-yl)-; 945244-45-1; FCAS 945244-45-1
EINECS	Contact for details

Quality Control

Our 1-(6-Fluorobenzo[D][1,3]Dioxol-5-Yl)Cyclopropanecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical and agrochemical research. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available for every lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.