Description

4-(2-Bromophenoxy)-3-Chloroaniline is a specialized halogenated aniline derivative, serving as a crucial advanced intermediate in modern synthetic chemistry. Its molecular structure, featuring both bromophenoxy and chloro-substituted aniline moieties, makes it a versatile building block for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and industrial R&D departments engaged in the development of pharmaceuticals, agrochemicals, and functional materials, where precise structural modification is key to achieving desired biological or physical activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system disorders or possessing specific receptor binding profiles.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where its halogenated structure can contribute to enhanced efficacy and environmental stability.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, or organic electronic materials.
• Dye and Pigment Intermediate: Acts as a building block for synthesizing complex azo dyes and high-performance pigments, contributing to color fastness and specific spectral properties.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) due to the presence of bromine and amine functional groups, enabling rapid diversification of chemical libraries.

Basic Information

Item	Details
Product Name	4-(2-Bromophenoxy)-3-Chloroaniline
CAS No.	945006-23-5
Molecular Formula	C12H9BrClNO
Molecular Weight	298.56 g/mol
Synonyms	3-Chloro-4-(2-bromophenoxy)aniline; 4-(2-Bromophenoxy)-3-chlorobenzenamine; Benzenamine, 3-chloro-4-(2-bromophenoxy)-; 3-Chloro-4-(o-bromophenoxy)aniline; 4-(2-Bromophenoxy)-3-chloro-phenylamine; (3-Chloro-4-((2-bromophenoxy)phenyl)amine
EINECS	Contact for details

Quality Control

Every batch of 4-(2-Bromophenoxy)-3-Chloroaniline is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and scale-up activities. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, and custom specifications can be developed to support specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.