Description

5-Chloropyrimidine-2-Carbaldehyde is a versatile and high-value heterocyclic building block, essential for advanced organic synthesis. Its core value lies in its bifunctional reactivity, featuring both an electrophilic chloro substituent and a reactive aldehyde group, enabling precise molecular construction. This compound is critically needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors, antiviral agents, and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators, leveraging the pyrimidine core's bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized chelating ligands, organocatalysts, and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers, organic semiconductors, and advanced organic materials with tailored electronic properties.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom chemical synthesis services, supporting R&D and scale-up projects.
• Academic & Institutional Research: Used in universities and research institutes for methodological studies in heterocyclic and medicinal chemistry.

Basic Information

Product Name	5-Chloropyrimidine-2-Carbaldehyde
CAS No.	944900-20-3
Molecular Formula	C5H3ClN2O
Molecular Weight	142.54 g/mol
Synonyms	2-Formyl-5-chloropyrimidine; 5-Chloro-2-pyrimidinecarboxaldehyde; 5-Chloro-2-formylpyrimidine; 5-Chloropyrimidine-2-carboxaldehyde; 944900-20-3; 5-Chloro-2-pyrimidinecarbaldehyde; 5-Chloro-pyrimidine-2-carbaldehyde
EINECS	Contact for details

Quality Control

Our 5-Chloropyrimidine-2-Carbaldehyde is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, GC, NMR, and MS, for comprehensive identity confirmation and impurity profiling. A Certificate of Analysis (COA) detailing purity, assay, and specific test results is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity, the container should be kept under an inert atmosphere (e.g., nitrogen) to prevent oxidation and moisture uptake. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.