Description

(1S,4As,8As)-1-Hydroxy-5,5,8A-Trimethyl-4A,6,7,8-Tetrahydro-4H-Naphtha Lene-1,2-Dicarbaldehyde is a high-purity, functionalized naphthalene derivative with a complex stereochemistry that makes it a valuable chiral building block in advanced organic synthesis. Its structure, featuring both aldehyde and hydroxyl functional groups, provides versatile reactivity for constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and fine chemical industries seeking to develop novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Advanced Organic Synthesis: Used as a sophisticated building block for constructing complex natural product analogs and complex heterocyclic compounds.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in the development of new stereoselective catalytic reactions.
• Fine Chemical Production: Integral in the manufacture of high-value specialty chemicals, including flavors, fragrances, and advanced polymers.
• Material Science Research: Investigated for its potential in creating novel organic electronic materials or metal-organic frameworks (MOFs) due to its rigid, functionalized core.
• Agrochemical Intermediate: Used in the research and development of new, more effective crop protection agents with specific stereochemical requirements.

Basic Information

Product Name	(1S,4As,8As)-1-Hydroxy-5,5,8A-Trimethyl-4A,6,7,8-Tetrahydro-4H-Naphtha Lene-1,2-Dicarbaldehyde
CAS No.	10-25-3
Molecular Formula	C15H20O3
Molecular Weight	248.32 g/mol
Synonyms	1,2-Diformyl-1-hydroxy-5,5,8a-trimethyl-decahydronaphthalene; (1S,4aR,8aS)-1-Hydroxy-5,5,8a-trimethyl-1,2,3,4,4a,5,6,7,8,8a-decahydronaphthalene-1,2-dicarbaldehyde; 1-Hydroxy-5,5,8a-trimethyl-decahydronaphthalene-1,2-dicarbaldehyde; Trimethyl-decahydronaphthalene-dicarbaldehyde; Chiral Naphthalene Dialdehyde Derivative
EINECS	Contact for details

Quality Control

Our (1S,4As,8As)-1-Hydroxy-5,5,8A-Trimethyl-4A,6,7,8-Tetrahydro-4H-Naphtha Lene-1,2-Dicarbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure high chemical and stereochemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This compound is easily oxidized and light-sensitive; allow the container to reach room temperature before opening to minimize moisture condensation and oxidative degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.