Description

5-Fluoro-1,3-Benzoxazole-2-Carboxylic Acid is a high-value fluorinated heterocyclic building block essential for advanced organic synthesis. This compound serves as a critical precursor in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique benzoxazole scaffold and carboxylic acid functionality enable precise molecular modifications. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorinated benzoxazole moiety.
• Organic Synthesis Building Block: Serves as a versatile starting material for constructing complex heterocyclic systems and functionalized molecules in academic and industrial research.
• Material Science Precursor: Potential use in the synthesis of specialty polymers, ligands for catalysis, or organic electronic materials due to its rigid aromatic structure.

Basic Information

Product Name	5-Fluoro-1,3-Benzoxazole-2-Carboxylic Acid
CAS No.	944898-49-1
Molecular Formula	C8H4FNO3
Molecular Weight	181.12 g/mol
Synonyms	5-Fluorobenzoxazole-2-carboxylic acid; 2-Carboxy-5-fluorobenzoxazole; 5-Fluoro-2-benzoxazolecarboxylic acid; 5-Fluoro-1,3-benzoxazole-2-carboxylic acid; 944898-49-1; 5-Fluoro-benzooxazole-2-carboxylic acid; 5-Fluoro-2-carboxybenzoxazole
EINECS	Contact for details

Quality Control

Our 5-Fluoro-1,3-Benzoxazole-2-Carboxylic Acid is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and scale-up. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as purity (by HPLC), identity confirmation, and impurity profiles. Our quality system is designed to meet the stringent requirements of pharmaceutical and agrochemical development partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed and away from direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.