Description

5-Trifluoromethyl-Imidazo[1,2-A]Pyridine is a high-value, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core structure combines an imidazopyridine scaffold with a strategically positioned trifluoromethyl group, offering unique electronic and steric properties for modulating the bioactivity and physicochemical profile of target molecules. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in therapeutic areas targeting the central nervous system, oncology, and infectious diseases.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group can enhance lipophilicity and metabolic stability.
• Material Science Precursor: Serves as a building block for advanced organic electronic materials, such as ligands for catalysts or components in organic light-emitting diodes (OLEDs).
• Chemical Biology Probe: Employed in the design of molecular probes and tags for studying biological processes and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	5-Trifluoromethyl-Imidazo[1,2-A]Pyridine
CAS No.	944580-80-7
Molecular Formula	C8H5F3N2
Molecular Weight	186.14 g/mol
Synonyms	5-(Trifluoromethyl)imidazo[1,2-a]pyridine; Imidazo[1,2-a]pyridine, 5-(trifluoromethyl)-; 5-Trifluoromethylimidazo[1,2-a]pyridine; 5-CF3-Imidazo[1,2-a]pyridine; 5-(Trifluoromethyl)-1H-imidazo[1,2-a]pyridine; 5-Trifluoromethyl-1H-imidazo[1,2-a]pyridine
EINECS	Contact for details

Quality Control

Our 5-Trifluoromethyl-Imidazo[1,2-A]Pyridine is manufactured under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) detailing all specifications is available with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and stored away from direct light and moisture sources.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.