Description

Chloro{(S)-(-)-5,5'-Bis[Di(3,5-Xylyl)Phosphino]-4,4'-Bi-1,3-Benzodioxole} (p-Cymene)Ruthenium(Ii)Chloride[Rucl(p-Cymene)((S)-Dm-Segphos)]Cl is a high-value, chiral ruthenium complex specifically designed for asymmetric catalysis. This compound matters because it serves as a highly efficient and selective catalyst for a range of critical hydrogenation and transfer hydrogenation reactions, enabling the production of enantiomerically pure intermediates. It is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemical control to synthesize complex chiral molecules.

Application

• Asymmetric Hydrogenation Catalyst: For the enantioselective reduction of ketones, imines, and functionalized olefins to produce chiral alcohols, amines, and other building blocks.
• Pharmaceutical Intermediate Synthesis: Key for manufacturing active pharmaceutical ingredients (APIs) requiring high enantiomeric excess (ee), such as chiral amines and amino acid derivatives.
• Agrochemical Production: Used in the synthesis of chiral herbicides, fungicides, and plant growth regulators.
• Fine Chemical and Fragrance Manufacturing: Enables the production of high-value chiral flavors, fragrances, and specialty chemicals.
• Academic and Industrial R&D: A vital tool for methodological development in organic synthesis and catalysis research.
• Transfer Hydrogenation Reactions: Catalyzes reactions using alternative hydrogen donors like formic acid or isopropanol.

Basic Information

Product Name	Chloro{(S)-(-)-5,5'-Bis[Di(3,5-Xylyl)Phosphino]-4,4'-Bi-1,3-Benzodioxole} (p-Cymene)Ruthenium(Ii)Chloride[Rucl(p-Cymene)((S)-Dm-Segphos)]Cl
CAS No.	944451-31-4
Molecular Formula	C71H68Cl2O4P2Ru
Molecular Weight	~1216.58 g/mol
Synonyms	RuCl(p-cymene)[(S)-DM-SEGPHOS] chloride; [RuCl((S)-DM-SEGPHOS)(p-cymene)]Cl; (S)-(-)-5,5'-Bis[di(3,5-xylyl)phosphino]-4,4'-bi-1,3-benzodioxole (p-cymene)ruthenium(II) chloride; (S)-DM-SEGPHOS Ru(II) p-cymene chloride complex; Ruthenium-DM-SEGPHOS catalyst; Asymmetric hydrogenation catalyst Ru-SEGPHOS; Chiral ruthenium phosphine complex
EINECS	Contact for details

Quality Control

Our Chloro{(S)-(-)-5,5'-Bis[Di(3,5-Xylyl)Phosphino]-4,4'-Bi-1,3-Benzodioxole} (p-Cymene)Ruthenium(Ii)Chloride[Rucl(p-Cymene)((S)-Dm-Segphos)]Cl is manufactured under strict quality protocols. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and elemental analysis, to confirm identity, purity, and chiral integrity. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and batch-to-batch consistency for your critical catalytic processes.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to maintain stability and prevent oxidation and decomposition. Allow the container to reach room temperature in a dry environment before opening to minimize moisture exposure.

Specification

Item	Specification
Appearance	Orange to red-brown crystalline powder or solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Chiral Purity (HPLC)	≥ 99% ee
Ruthenium Content	Contact for details
Solubility	Soluble in dichloromethane, toluene, THF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.