Description

Chloro{(R)-(+)-5,5'-Bis[Di(3,5-Xylyl)Phosphino]-4,4'-Bi-1,3-Benzodioxole} (p-Cymene)Ruthenium(II)Chloride[Rucl(p-Cymene)((R)-Dm-Segphos)]Cl is a high-purity, chiral ruthenium complex designed for advanced asymmetric catalysis. This compound is a critical precatalyst for achieving high enantioselectivity in a variety of synthetic transformations, enabling the production of optically pure intermediates. It is essential for R&D and production chemists in the pharmaceutical and fine chemical industries who require reliable and efficient chiral catalysts.

Application

• Asymmetric Hydrogenation: A highly effective catalyst for the enantioselective reduction of functionalized olefins, ketones, and imines to produce chiral alcohols and amines.
• Pharmaceutical Intermediate Synthesis: Key for constructing chiral centers in active pharmaceutical ingredients (APIs), including those for cardiovascular, CNS, and antiviral drugs.
• Fine Chemical Production: Used in the synthesis of specialty chemicals, flavors, fragrances, and agrochemicals where optical purity is paramount.
• Academic & Industrial R&D: A valuable tool for method development and exploring new asymmetric catalytic reactions in laboratory settings.
• Process Chemistry Optimization: Employed to scale up efficient and selective synthetic routes from bench to pilot plant and commercial production.

Basic Information

Product Name	Chloro{(R)-(+)-5,5'-Bis[Di(3,5-Xylyl)Phosphino]-4,4'-Bi-1,3-Benzodioxole} (p-Cymene)Ruthenium(II)Chloride[Rucl(p-Cymene)((R)-Dm-Segphos)]Cl
CAS No.	944451-30-3
Molecular Formula	C71H68Cl2O4P2Ru
Molecular Weight	1190.58 g/mol
Synonyms	(R)-DM-SEGPHOS Ru(p-cymene) chloride; [RuCl((R)-DM-SEGPHOS)(p-cymene)]Cl; Ruthenium, chloro[(1,2,3,4,5,6-η)-1-methyl-4-(1-methylethyl)benzene][(5,5′-bi-1,3-benzodioxole)-4,4′-diylbis[di(3,5-dimethylphenyl)phosphine]]-, chloride, (R)-; (R)-RuCl(p-cymene)(DM-SEGPHOS) chloride; (R)-DM-SEGPHOS Ru(II) (p-cymene) chloride complex; Asymmetric hydrogenation catalyst Ru-DM-SEGPHOS; Ru/(R)-DM-SEGPHOS catalyst.
EINECS	Contact for details

Quality Control

Every batch of our chiral ruthenium catalyst is manufactured and tested under strict quality protocols to ensure consistent high performance and enantioselectivity. Our products undergo rigorous quality testing, including advanced spectroscopic and chromatographic methods, to ensure compliance with research and process chemistry standards. Comprehensive Certificates of Analysis (COA) detailing purity, chiral integrity, and metal content are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a dry, cool place. This compound is strictly light-sensitive, easily oxidized, and hygroscopic. Allow the sealed container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Orange to red-brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Ruthenium Content	Contact for details
Solubility	Soluble in dichloromethane, toluene, THF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.