Description

2-(Difluoromethyl)Benzylamine is a versatile aromatic amine building block featuring a difluoromethyl substituent, which imparts unique physicochemical properties critical for advanced synthesis. This compound is essential for researchers and manufacturers requiring a high-purity intermediate to introduce both amine and fluorinated motifs into target molecules. It is primarily utilized in the development of active pharmaceutical ingredients (APIs), agrochemicals, and functional materials where its structural features can enhance metabolic stability and binding affinity.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel drug candidates, particularly in medicinal chemistry for creating molecules with improved pharmacokinetic profiles.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the difluoromethyl group can contribute to biological activity and environmental stability.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis.
• Material Science: Employed in the synthesis of specialty polymers, resins, or liquid crystals that benefit from fluorine incorporation.
• Chemical Research & Development: A valuable building block for constructing complex organic frameworks in academic and industrial R&D settings.
• Fluorinated Compound Library: Integral for combinatorial chemistry and high-throughput screening to discover new bioactive compounds.

Basic Information

Item	Details
Product Name	2-(Difluoromethyl)Benzylamine
CAS No.	944386-58-7
Molecular Formula	C8H9F2N
Molecular Weight	157.16 g/mol
Synonyms	1-(Aminomethyl)-2-(difluoromethyl)benzene; (2-(Difluoromethyl)phenyl)methanamine; α-(Difluoromethyl)benzylamine; 2-(Difluoromethyl)benzenemethanamine; 2-(Difluoromethyl)-benzylamine; Benzylamine, 2-(difluoromethyl)-; 2-(Difluoromethyl)benzyl amine
EINECS	Contact for details

Quality Control

Our 2-(Difluoromethyl)Benzylamine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere such as nitrogen to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.