Description

4-Bromo-1-Fluoro-2-Isopropoxybenzene is a high-purity halogenated aromatic ether building block of significant value in advanced organic synthesis. Its unique structure, featuring bromine, fluorine, and an isopropoxy group on a benzene ring, makes it a versatile intermediate for constructing complex molecules. This compound is primarily sought after by R&D and production chemists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in the synthesis of fluorinated drug candidates where the fluorine atom can enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the halogenated aromatic core for biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated aromatic compounds used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Stille) to form biaryl structures.
• Chemical Research & Development: Employed as a versatile building block in academic and industrial R&D for exploring new chemical entities and synthetic pathways.
• Functional Material Precursor: Used in the synthesis of specialized polymers, ligands for catalysis, and other performance materials requiring a halogenated, ether-functionalized aromatic system.

Basic Information

Product Name	4-Bromo-1-Fluoro-2-Isopropoxybenzene
CAS No.	944278-95-9
Molecular Formula	C9H10BrFO
Molecular Weight	233.08 g/mol
Synonyms	1-Bromo-4-fluoro-2-isopropoxybenzene; 2-Isopropoxy-4-bromofluorobenzene; 4-Bromo-2-isopropoxyfluorobenzene; 2-Fluoro-5-bromophenyl isopropyl ether; 1-Fluoro-4-bromo-2-isopropoxybenzene; Benzene, 4-bromo-1-fluoro-2-(1-methylethoxy)-; 944278-95-9
EINECS	Contact for details

Quality Control

Our 4-Bromo-1-Fluoro-2-Isopropoxybenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurity profile, and physical characteristics are provided with every shipment to guarantee consistent quality and traceability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.