Description

2-Iodo-4-Thiazolecarboxylic Acid is a high-value halogenated heterocyclic building block, specifically engineered for advanced organic synthesis. This compound is critical for researchers and manufacturers requiring precise molecular modifications to develop novel active compounds. It is primarily utilized in the pharmaceutical and agrochemical industries for the synthesis of complex molecules, including potential drug candidates and specialized chemical intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for molecules containing the thiazole scaffold.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides where the iodo-thiazole moiety imparts specific biological activity.
• Material Science Research: Serves as a precursor for functionalized materials, including liquid crystals and organic semiconductors.
• Cross-Coupling Reactions: An essential substrate for palladium-catalyzed reactions like Suzuki, Stille, or Sonogashira couplings, enabling complex carbon-carbon bond formation.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-Iodo-4-Thiazolecarboxylic Acid
CAS No.	944275-17-6
Molecular Formula	C4H2INO2S
Molecular Weight	254.03 g/mol
Synonyms	4-Thiazolecarboxylic acid, 2-iodo-; 2-Iodothiazole-4-carboxylic acid; 2-Iodo-1,3-thiazole-4-carboxylic acid; 2-Iodo-4-carboxythiazole; Iodothiazolecarboxylic acid; 944275-17-6; 2-Iodo-4-thiazolecarboxylate
EINECS	Contact for details

Quality Control

Our 2-Iodo-4-Thiazolecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and NMR/IR for structural confirmation, to ensure it meets the stringent requirements for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.