Description

3-(n-Ethylaminocarbonyl)Phenylboronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the precise construction of complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for drug discovery and development.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of biaryl compounds, a common scaffold in active pharmaceutical ingredients (APIs).
• Pharmaceutical Intermediate: Used in the research and development of novel drug candidates, particularly in creating complex, functionalized aromatic systems.
• Agrochemical Synthesis: Employed in the production of advanced herbicides, fungicides, and insecticides that require specific aryl-boronate intermediates.
• Material Science Research: Acts as a monomer or precursor in the development of organic electronic materials, such as polymers for OLEDs and OFETs.
• Chemical Biology & Proteomics: Utilized in the synthesis of molecular probes and activity-based protein profiling (ABPP) reagents due to its reactive boronate handle.
• Scale-up Process Chemistry: The pinacol ester protection offers enhanced stability, making it suitable for multi-step synthesis and kilogram-scale manufacturing processes.

Basic Information

Product Name	3-(n-Ethylaminocarbonyl)Phenylboronic Acid Pinacol Ester
CAS No.	943911-67-9
Molecular Formula	C15H22BNO3
Molecular Weight	275.15 g/mol
Synonyms	[3-(Ethylcarbamoyl)phenyl]boronic acid pinacol ester; 3-(Ethylaminocarbonyl)benzeneboronic acid pinacol ester; N-Ethyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide; 3-Carbamoylphenylboronic acid pinacol ester, N-ethyl derivative; B-[3-(Ethylaminocarbonyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 943911-67-9; Boronic acid, B-[3-[(ethylamino)carbonyl]phenyl]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 3-(n-Ethylaminocarbonyl)Phenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.