Description

Benzene, 1-Chloro-3,5-Difluoro-2-Methoxy- is a high-purity, multi-substituted aromatic building block of significant importance in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. Industrial and research chemists need it for constructing active pharmaceutical ingredients (APIs), liquid crystal materials, and specialized agrochemicals where precise halogen and methoxy substitution patterns are critical.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing novel drug candidates, especially in fluorinated pharmaceutical chemistry.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides that benefit from its unique halogenated structure.
• Liquid Crystal Materials: Serves as a core component in the synthesis of fluorinated liquid crystals for display technologies.
• Organic Electronic Materials: Employed in the research and development of organic semiconductors and electro-optical materials.
• Chemical Research & Development: A versatile reagent for method development and exploring new reactions in organofluorine chemistry.
• Custom Synthesis: Used by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule construction.

Basic Information

Product Name	Benzene, 1-Chloro-3,5-Difluoro-2-Methoxy-
CAS No.	943830-21-5
Molecular Formula	C7H5ClF2O
Molecular Weight	178.56 g/mol
Synonyms	1-Chloro-3,5-difluoro-2-methoxybenzene; 2-Methoxy-1-chloro-3,5-difluorobenzene; 3,5-Difluoro-2-methoxychlorobenzene; 1-Chloro-2-methoxy-3,5-difluorobenzene; 2-Chloro-1,3-difluoro-4-methoxybenzene (isomer reference); 3,5-Difluoro-2-methoxyphenyl chloride; Difluoromethoxychlorobenzene
EINECS	Contact for details

Quality Control

Our Benzene, 1-Chloro-3,5-Difluoro-2-Methoxy- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment aligns with cGMP standards where applicable, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; ensure containers are kept tightly sealed to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.35 g/cm³
Boiling Point	~185-190°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.