Description

Alpha, α- Two Fluorine -6- Methyl Ester Of Acetic Acid is a specialized fluorinated acetic acid ester, a high-value intermediate in advanced organic synthesis. Its molecular structure, featuring fluorine atoms, is critical for modifying the physicochemical properties of target molecules, enhancing metabolic stability and lipophilicity. This compound is essential for R&D and production chemists in the pharmaceutical and agrochemical industries seeking to develop novel active ingredients with improved performance profiles.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly for candidates in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine moiety can increase biological activity and environmental persistence.
• Material Science Precursor: Serves as a monomer or modifier in the development of specialty polymers and coatings with enhanced chemical resistance and surface properties.
• Liquid Crystal & Electronic Chemicals: Employed in the synthesis of fluorinated components for liquid crystal displays (LCDs) and dielectric materials.
• Organic Synthesis Reagent: Acts as a versatile fluorinating agent or protecting group in complex multi-step synthetic routes for fine chemicals.
• Positron Emission Tomography (PET) Tracer Development: Potential use as a precursor for incorporating fluorine-18 radioisotopes, crucial for developing diagnostic imaging agents.

Basic Information

Product Name	Alpha, α- Two Fluorine -6- Methyl Ester Of Acetic Acid
CAS No.	943541-38-6
Molecular Formula	C5H6F2O2
Molecular Weight	136.10 g/mol
Synonyms	2,2-Difluoro-6-methyl acetate; Methyl 2,2-difluoroacetate; Difluoroacetic acid methyl ester; Methyl difluoroacetate; 2,2-Difluoroacetic acid methyl ester; Acetic acid, 2,2-difluoro-, methyl ester; Methyl 2,2-difluoroethanoate
EINECS	Contact for details

Quality Control

Our Alpha, α- Two Fluorine -6- Methyl Ester Of Acetic Acid is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including GC/HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets precise customer specifications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for prolonged storage to maintain purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Total impurities ≤ 2.0%
Density (at 20°C)	1.20 - 1.30 g/mL
Refractive Index (n20D)	1.350 - 1.370

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.