Description

1-Difluoromethyl-3,5-Dimethyl-1H-Pyrazole-4-Sulfonyl Chloride is a high-purity, multi-functional chemical building block essential for advanced organic synthesis. This compound is valued for its reactive sulfonyl chloride group and the unique difluoromethyl moiety, enabling precise molecular modifications. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting metabolic and central nervous system disorders.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the difluoromethyl group can enhance biological activity and stability.
• Material Science Research: Serves as a building block for creating specialized polymers and functional materials with tailored surface properties.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and labeling reagents for biochemical research and diagnostic applications.
• Cross-Coupling Reactions: Acts as an electrophilic coupling partner in palladium-catalyzed and other metal-mediated cross-coupling reactions to construct complex heterocycles.

Basic Information

Product Name	1-Difluoromethyl-3,5-Dimethyl-1H-Pyrazole-4-Sulfonyl Chloride
CAS No.	943152-92-9
Molecular Formula	C6H7ClF2N2O2S
Molecular Weight	236.65 g/mol
Synonyms	1-(Difluoromethyl)-3,5-dimethyl-1H-pyrazole-4-sulfonyl chloride; 3,5-Dimethyl-1-(difluoromethyl)-1H-pyrazole-4-sulfonyl chloride; 4-Sulfonyl chloride-1-difluoromethyl-3,5-dimethylpyrazole; Pyrazole-4-sulfonyl chloride, 1-(difluoromethyl)-3,5-dimethyl-; DFMP-SCl
EINECS	Contact for details

Quality Control

Our 1-Difluoromethyl-3,5-Dimethyl-1H-Pyrazole-4-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting full specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.