Description

1-Chloromethyl-5-Methyl-3-Nitro-1H-Pyrazole is a high-purity, versatile heterocyclic building block of significant importance in advanced organic synthesis. Its reactive chloromethyl and nitro functional groups make it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Serves as a building block for creating new pesticides, herbicides, and fungicides with enhanced efficacy.
• Material Science Research: Used in the development of advanced polymers, ligands, and functional materials.
• Chemical Biology & Proteomics: Employed as a reagent for bioconjugation and the development of chemical probes.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific pyrazole derivatives.

Basic Information

Product Name	1-Chloromethyl-5-Methyl-3-Nitro-1H-Pyrazole
CAS No.	943107-59-3
Molecular Formula	C5H6ClN3O2
Molecular Weight	175.57 g/mol
Synonyms	5-Methyl-3-nitro-1H-pyrazole-1-methanol, chloride; 1-(Chloromethyl)-5-methyl-3-nitro-1H-pyrazole; 1H-Pyrazole-1-methanol, 5-methyl-3-nitro-, chloride; 3-Nitro-5-methyl-1H-pyrazole-1-ylmethyl chloride; 1-Chloromethyl-3-nitro-5-methylpyrazole; Pyrazole derivative CAS 943107-59-3
EINECS	Contact for details

Quality Control

Our 1-Chloromethyl-5-Methyl-3-Nitro-1H-Pyrazole is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with each shipment, detailing all specifications and test results. We adhere to cGMP standards for pharmaceutical-grade intermediates, ensuring reliability for critical research and production applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.