Description

3,3,3-Trifluoro-1-Phenylpropan-1-Amine is a high-purity fluorinated aromatic amine building block of significant interest in advanced organic synthesis. Its value lies in the unique combination of a reactive primary amine group and a trifluoromethyl moiety, which can dramatically alter the physicochemical properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors seeking to incorporate fluorine for enhanced metabolic stability, lipophilicity, or electronic effects.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in CNS and oncology research where fluorine substitution is critical.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group for improved biological activity and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials, where it can influence dielectric anisotropy and stability.
• Polymer & Resin Modifier: Incorporated into specialty polymers to enhance chemical resistance, thermal stability, and surface properties.
• Fluorinated Ligand Precursor: Utilized in organometallic chemistry and catalysis to create novel ligands for transition metal complexes.
• Advanced Material Research: Employed in R&D for novel fluorinated compounds with applications in coatings, adhesives, and nanotechnology.

Basic Information

Product Name	3,3,3-Trifluoro-1-Phenylpropan-1-Amine
CAS No.	942996-06-7
Molecular Formula	C9H8F3N
Molecular Weight	187.16 g/mol
Synonyms	3,3,3-Trifluoro-1-phenylpropan-1-amine; 1-Phenyl-3,3,3-trifluoropropan-1-amine; α-(Trifluoromethyl)phenethylamine; Benzenepropanamine, 3,3,3-trifluoro-; 3,3,3-Trifluoropropylamine, 1-phenyl-; (3,3,3-Trifluoro-1-phenylpropyl)amine; γ,γ,γ-Trifluorophenethylamine
EINECS	Contact for details

Quality Control

Our 3,3,3-Trifluoro-1-Phenylpropan-1-Amine is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.