Description

12-Hydroxyganoderic Acid D is a bioactive triterpenoid compound primarily isolated from the medicinal mushroom *Ganoderma lucidum* (Reishi). This specific ganoderic acid derivative is of significant interest for its potential pharmacological properties and serves as a key reference standard in analytical and research settings. It is sought after by researchers and manufacturers in the nutraceutical, pharmaceutical, and advanced life science sectors for product development, quality control, and biological activity studies.

Application

• Pharmaceutical Research & Development: Used as a reference standard and active pharmaceutical ingredient (API) intermediate in the development of novel therapeutics targeting inflammation and metabolic disorders.
• Nutraceutical Standardization: Serves as a critical marker compound for the quality control, standardization, and potency verification of *Ganoderma lucidum* (Reishi) extracts and finished dietary supplements.
• Biological Activity Studies: Employed in *in vitro* and *in vivo* research to investigate its potential anti-inflammatory, hepatoprotective, anti-tumor, and immunomodulatory effects.
• Analytical Chemistry: Essential as a high-purity calibration standard for analytical methods such as HPLC, LC-MS, and TLC in laboratories for compound identification and quantification.
• Cosmeceutical Formulations: Incorporated into advanced skincare products for its potential antioxidant and anti-aging properties.
• Academic & Institutional Research: Used by universities and research institutes for biochemical pathway studies and the synthesis of novel derivatives.

Basic Information

Product Name	12-Hydroxyganoderic Acid D
CAS No.	942950-96-1
Molecular Formula	C30H44O8
Molecular Weight	532.67 g/mol
Synonyms	12α-Hydroxyganoderic acid D; Ganoderic acid DM; (3β,12α,15β,20S,24S)-12,15,20,24-Tetrahydroxy-3-(2-hydroxyacetyl)-lanosta-7,9(11)-dien-26-oic acid; 12-Hydroxy-GA D; Reishi Triterpenoid D; Ganoderma Triterpene D; 12-HGA D
EINECS	Contact for details

Quality Control

Our 12-Hydroxyganoderic Acid D is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and MS for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing all critical quality attributes to ensure compliance with your research or manufacturing specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.