Description

(E)-3-(5-Chloro-2-Tetrazol-1-Yl-Phenyl)-Acrylic Acid is a high-value, non-natural amino acid derivative featuring a tetrazole ring and an acrylic acid moiety, making it a versatile synthetic intermediate. This compound is critical for researchers and manufacturers requiring precise molecular scaffolds for advanced material and pharmaceutical development. It is primarily utilized in the synthesis of active pharmaceutical ingredients (APIs), agrochemicals, and as a key building block in medicinal chemistry for structure-activity relationship (SAR) studies.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel drug candidates, particularly those targeting specific enzyme receptors where the tetrazole group acts as a bioisostere for a carboxylic acid.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its unique heterocyclic structure for enhanced biological activity.
• Material Science: Acts as a monomer or cross-linking agent in the production of specialty polymers with specific optical or electronic properties.
• Medicinal Chemistry & SAR Studies: Essential for constructing complex molecular libraries to explore and optimize the pharmacokinetic and pharmacodynamic properties of lead compounds.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target identification.

Basic Information

Product Name	(E)-3-(5-Chloro-2-Tetrazol-1-Yl-Phenyl)-Acrylic Acid
CAS No.	942316-73-6
Molecular Formula	C₁₀H₇ClN₄O₂
Molecular Weight	250.64 g/mol
Synonyms	(E)-3-[5-Chloro-2-(1H-tetrazol-1-yl)phenyl]acrylic acid; (E)-3-(5-Chloro-2-(1H-tetrazol-1-yl)phenyl)-2-propenoic acid; 5-Chloro-2-(1H-tetrazol-1-yl)cinnamic acid; 942316-73-6; (E)-3-(5-Chloro-2-tetrazol-1-ylphenyl)prop-2-enoic acid; 3-(5-Chloro-2-(1H-tetrazol-1-yl)phenyl)acrylic acid
EINECS	Contact for details

Quality Control

Our (E)-3-(5-Chloro-2-Tetrazol-1-Yl-Phenyl)-Acrylic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and hygroscopic; therefore, handling under an inert atmosphere is recommended for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.