Description

2-Phenyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Oxazole is a high-value boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require precise and scalable synthesis of advanced intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drug candidates containing oxazole and biaryl motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific heterocyclic architectures.
• Material Science Research: Building block for creating organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, where the oxazole-boronate unit modulates electronic properties.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and tags for imaging and diagnostic applications.
• Academic & R&D Laboratories: A versatile reagent for methodological development in cross-coupling and heterocyclic chemistry.
• Scale-up Process Chemistry: Suitable for transitioning from milligram-scale discovery to kilogram-scale production under optimized coupling conditions.

Basic Information

Product Name	2-Phenyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Oxazole
CAS No.	942070-80-6
Molecular Formula	C15H18BNO3
Molecular Weight	271.12 g/mol
Synonyms	2-Phenyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-oxazole; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-phenyloxazole; 2-Phenyloxazole-5-boronic acid pinacol ester; Oxazole-5-boronic acid, 2-phenyl-, pinacol ester; 942070-80-6; 2-Phenyl-5-(pinacolatoboryl)oxazole
EINECS	Contact for details

Quality Control

Our 2-Phenyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Oxazole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR, HPLC, and mass spectrometry, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.