Description

1-Methyl-1H-Imidazole-5-Boronic Acid Pinacol Ester is a high-value organoboron building block, specifically a protected boronic acid derivative, essential for modern synthetic chemistry. Its primary value lies in enabling Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules with high efficiency and selectivity. This compound is critically needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for developing new active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly those containing imidazole heterocycles, for targets in oncology, CNS, and anti-infective therapies.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science: Employed in the creation of organic electronic materials, such as ligands for OLEDs and conductive polymers.
• Chemical Biology & Proteomics: Serves as a versatile handle for bioconjugation and the development of enzyme inhibitors or molecular probes.
• Academic & Contract Research: A fundamental reagent for methodological development in organic synthesis and catalysis research within R&D laboratories.
• Scale-up Process Chemistry: Suitable for optimization and pilot-scale production of target molecules due to its stability and reactivity profile.

Basic Information

Item	Details
Product Name	1-Methyl-1H-Imidazole-5-Boronic Acid Pinacol Ester
CAS No.	942070-72-6
Molecular Formula	C11H19BN2O2
Molecular Weight	222.10 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-methyl-1H-imidazole; 1-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-imidazole; 1-Methyl-1H-imidazole-5-boronic acid pinacol ester; 1-Methylimidazole-5-boronic acid pinacol ester; 5-Borono-1-methylimidazole, pinacol ester; (1-Methyl-1H-imidazol-5-yl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 1-Methyl-1H-Imidazole-5-Boronic Acid Pinacol Ester is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.