Description

1-Benzyl-1H-Imidazole-5-Boronic Acid Pinacol Ester is a high-value, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex heterocyclic scaffolds. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for drug discovery and fine chemical synthesis.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between aryl/heteroaryl halides and the imidazole ring system.
• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing benzyl-imidazole pharmacophores.
• Agrochemical Synthesis: Serves as a building block for creating novel fungicides, herbicides, and insecticides with specific biological activity.
• Ligand and Catalyst Development: Employed in the preparation of specialized N-heterocyclic ligands for metal catalysis.
• Material Science Research: Used to synthesize organic electronic materials, such as components for OLEDs or conductive polymers.
• Chemical Biology Probes: Facilitates the creation of tagged molecules for studying biological processes and protein interactions.

Basic Information

Item	Detail
Product Name	1-Benzyl-1H-Imidazole-5-Boronic Acid Pinacol Ester
CAS No.	942070-62-4
Molecular Formula	C₁₆H₂₁BN₂O₂
Molecular Weight	284.16 g/mol
Synonyms	1-Benzyl-1H-imidazole-5-boronic acid pinacol ester; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-benzyl-1H-imidazole; 1-Benzyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-imidazole; 1-Benzyl-1H-imidazol-5-ylboronic acid pinacol ester; 1-Benzyl-5-(pinacolboranyl)imidazole; 942070-62-4; BRN 15412135
EINECS	Contact for details

Quality Control

Every batch of 1-Benzyl-1H-Imidazole-5-Boronic Acid Pinacol Ester is produced and tested under stringent quality management protocols to ensure consistency and reliability for your critical applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.