Description

7-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-c]pyridine is a high-value, heterocyclic boronic ester derivative, serving as a critical synthetic intermediate in modern organic chemistry. Its primary value lies in enabling efficient carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for the development of novel active pharmaceutical ingredients (APIs) and functional organic compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially those containing the pyrrolopyridine scaffold, which is prevalent in kinase inhibitors and other therapeutic agents.
• Agrochemical Research: Used in the discovery and development of new pesticides and herbicides, leveraging its ability to introduce complex heterocyclic structures into target molecules.
• Material Science: Serves as a precursor for creating organic electronic materials, such as those used in OLEDs (Organic Light-Emitting Diodes) and semiconductors, due to its conjugated system and functional handle.
• Chemical Synthesis: A versatile reagent in academic and industrial R&D for constructing complex, fused heterocyclic systems through palladium-catalyzed cross-coupling reactions.
• Ligand & Catalyst Development: Potential use in the synthesis of novel bidentate or tridentate ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	7-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-c]pyridine
CAS No.	942070-50-0
Molecular Formula	C13H16BClN2O2
Molecular Weight	278.54 g/mol
Synonyms	7-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-c]pyridine; 7-Chloro-1H-pyrrolo[2,3-c]pyridine-2-boronic acid pinacol ester; 7-Chloro-2-(pinacolboranyl)-1H-pyrrolo[2,3-c]pyridine; 7-Chloro-1H-pyrrolo[2,3-c]pyridine-2-boronic acid, pinacol ester; 942070-50-0; 7-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-c]pyridine; 7-Chloro-2-(pinacolatoboryl)-1H-pyrrolo[2,3-c]pyridine
EINECS	Contact for details

Quality Control

Our 7-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-c]pyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. All products undergo rigorous analytical testing, including HPLC, NMR, and LC-MS, to confirm identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Recommended storage temperature: 2-8°C (refrigerated) for optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.