Description

4,4,5,5-Tetramethyl-2-(5-Trimethylsilanyl-Thiophen-2-Yl)-[1,3,2]Dioxaborolane is a high-value, organoboron building block featuring a protected thiophene moiety. This compound is essential for Suzuki-Miyaura cross-coupling reactions, enabling the efficient synthesis of complex, sulfur-containing organic architectures. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates containing thiophene heterocycles.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides with tailored properties.
• Organic Electronics: Crucial precursor for manufacturing conjugated polymers and small molecules used in OLEDs, organic photovoltaics (OPVs), and field-effect transistors (OFETs).
• Material Science Research: Enables the creation of novel organic semiconductors, liquid crystals, and other functional materials with specific electronic properties.
• Chemical Synthesis: Serves as a versatile reagent in academic and industrial R&D for constructing complex, sulfur-based molecular scaffolds via palladium-catalyzed cross-coupling.
• Ligand and Catalyst Development: Used to synthesize sophisticated ligands and organometallic complexes for catalytic applications.

Basic Information

Product Name	4,4,5,5-Tetramethyl-2-(5-Trimethylsilanyl-Thiophen-2-Yl)-[1,3,2]Dioxaborolane
CAS No.	942070-36-2
Molecular Formula	C15H27BO2SSi
Molecular Weight	310.33 g/mol
Synonyms	2-(5-Trimethylsilylthiophen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trimethylsilyl)thiophene; 2-(5-Trimethylsilyl-2-thienyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 5-Trimethylsilyl-2-thiopheneboronic acid pinacol ester; Thiophene-2-boronic acid, 5-(trimethylsilyl)-, pinacol ester; 942070-36-2; TMS-Thiophene pinacol boronic ester
EINECS	Contact for details

Quality Control

Our 4,4,5,5-Tetramethyl-2-(5-Trimethylsilanyl-Thiophen-2-Yl)-[1,3,2]Dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR, HPLC, and GC analysis, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light) and should be handled under an inert atmosphere when appropriate to prevent degradation. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.