Description

3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thiophene-2-Carbonitrile is a high-purity, versatile boronic ester derivative, serving as a critical synthetic intermediate in modern organic chemistry. Its value lies in enabling efficient cross-coupling reactions, particularly Suzuki-Miyaura couplings, to construct complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality building blocks for drug discovery, ligand synthesis, and the development of functional organic electronics.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing thiophene and nitrile functional groups.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific heterocyclic frameworks.
• Material Science: Serves as a precursor for conjugated polymers and organic semiconductors used in OLEDs, OFETs, and solar cells.
• Chemical Research: A valuable reagent in academic and industrial R&D for constructing complex molecules via palladium-catalyzed cross-coupling reactions.
• Ligand & Catalyst Development: Employed in the synthesis of novel bidentate ligands and organometallic catalysts.
• Fine Chemical Production: Intermediate for the manufacture of specialty chemicals, dyes, and pigments.

Basic Information

Product Name	3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thiophene-2-Carbonitrile
CAS No.	942070-34-0
Molecular Formula	C11H14BNO2S
Molecular Weight	235.11 g/mol
Synonyms	2-Cyano-3-thienylboronic acid pinacol ester; Thiophene-2-carbonitrile, 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene-2-carbonitrile; 3-Thiopheneboronic acid, 2-cyano-, pinacol ester; 2-Cyanothiophene-3-boronic acid pinacol ester; 3-Borono-2-cyanothiophene pinacol ester; PINACOL 2-CYANOTHIOPHENE-3-BORONATE
EINECS	Contact for details

Quality Control

Our 3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thiophene-2-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance for critical synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.